Role of allergy in the development of alopecia areata

Alopecia areata is an autoimmune disease characterized by non-scarring hair loss with preservation of the follicle. Hair in alopecia can be either focal appearance clearly defined foci alopecia, or diffuse complete any area skin where follicles are present. Data on role food allergy development and nature sensitization spectrum extremely scarce. Objective: to study features pollen (cross-reacting) allergens patients areata. The involved (n = 17), who were divided into groups according age: group 1 — children 9) 2 adults 8). All underwent a specific allergological examination: collection allergic history, prick testing (Allergopharma, Germany). Analysis revealed depending their age. Thus, sick children, highest frequency whole chicken eggs, cereals, yeast, soybeans cow's milk proteins was noted. In adults, most significant were: egg protein, rye flour, oats. Among first patients, common mixture weed grass pollen, second group, meadow pollen. taking account testing, administered individual elimination diet exclusion causally allergens, crossreacting allergens. effect assessed months after start diet. 70% showed clinical improvement, i.e., growth vellus noted (vellus depigmented hair) as well terminal pigmented hair. Complete regression occurred average within 3-6 from therapy. positive our supports this disorder. Therefore, causal relationship between particular relevance creates prerequisites for discovery new diagnostic therapeutic options.